Orangeburg, South Carolina, is a hidden gem for travelers seeking a blend of comfort and Southern charm. This city offers a variety of hotels that cater to every type of visitor, whether you’re on a family vacation, a business trip, or just passing through. From well-known chains to cozy inns, you’ll find plenty of accommodations that make your stay enjoyable and convenient.
Staying in Orangeburg allows you to unwind in a welcoming atmosphere while being close to local attractions. Many hotels provide excellent amenities such as free Wi-Fi, complimentary breakfasts, and lovely pools. After a day of sightseeing or shopping, you can relax in your room or enjoy the friendly service that adds to the homey feel of this charming Southern town.
Best Hotels In Orangeburg, SC
1. Hampton Inn & Suites Orangeburg

Welcome to Hampton Inn & Suites Orangeburg! This hotel shines with a fantastic rating of 4.7/5 from over 750 reviews. Guests love the clean rooms and comfy beds, perfect for a restful night’s sleep after exploring.
Enjoy a splash in the outdoor pool or stay connected with free Wi-Fi. The hotel offers modern amenities to meet your every need. Start your day with a delicious complimentary breakfast featuring hot and cold options.
Location is key here! Situated near I-26, it provides easy access to local attractions and dining options. Explore the beautiful parks and historical sites nearby.
Relax in the cozy lobby or take a stroll in the calm surroundings. Helpful staff are always ready to make your stay enjoyable. Families and business travelers alike enjoy their time here.
If you’re looking for comfort and great service, Hampton Inn & Suites is the place to be. Rates vary, so check for the best deals!
Address: Near I-26, Orangeburg, SC
2. Tru By Hilton Orangeburg

Visit Tru By Hilton Orangeburg for a refreshing and modern experience. This hotel boasts a rating of 4.3/5, making it a popular choice for travelers. The design is sleek and appealing, creating a fun atmosphere.
Stay active at the well-equipped fitness center, or enjoy free Wi-Fi throughout the property. The colorful lobby invites you to relax and socialize. Guests love the creativity in the room layouts.
An excellent breakfast is served daily, offering a variety of options. Grab a bite before heading out to explore nearby SC State University and more.
Whether you’re here for business or leisure, Tru By Hilton caters to your needs. The friendly staff is always greeting with a smile, ensuring you feel at home.
Book your stay and dive into a world of comfort and style at Tru By Hilton Orangeburg.
Address: Near SC State University, Orangeburg, SC
3. SpringHill Suites by Marriott Orangeburg
Experience comfort at SpringHill Suites by Marriott Orangeburg. This all-suites hotel is perfect for families and long stays. Enjoy an indoor pool, which is a hit among guests of all ages.
Start your day with a complimentary breakfast featuring a range of delicious choices. Free high-speed Wi-Fi keeps you connected during your visit. The spacious suites provide any traveler with ample room to relax and unwind.
Conveniently located close to I-26, you can easily explore Orangeburg and surrounding attractions. Historical sites and natural beauty await just a short drive away.
The friendly team at SpringHill Suites will ensure your stay is memorable and enjoyable. Comfortable amenities cater to business and leisure guests alike.
Experience hospitality at its finest at SpringHill Suites by Marriott Orangeburg. Perfect for your next trip!
Address: 675 Citadel Road, Orangeburg, SC 29118
4. Suburban Studios
Welcome to Suburban Studios, rated 4.6/5 by guests. This hotel offers a unique experience with its kitchenette-equipped rooms, ideal for longer stays. Feel right at home with the convenience of in-room dining options.
Free Wi-Fi keeps you connected while you enjoy your trip. The pet-friendly policy makes it easier for guests traveling with furry companions. You can explore Orangeburg stress-free.
Located on Saint Matthews Road, it’s within easy reach of eateries and stores. The staff provides excellent service, making your stay comfortable and welcoming.
After a day of adventure, retreat to Suburban Studios to relax and recharge. The peaceful atmosphere is perfect for unwinding.
Experience value and comfort at Suburban Studios. Your satisfaction is the priority!
Address: 3671 Saint Matthews Road, Building B, Orangeburg, SC 29118
5. Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg is a fantastic place to stay! Rated highly by visitors, this hotel features family rooms and free Wi-Fi. A delicious breakfast is included to fuel your day.
Located on Citadel Road, its proximity to attractions makes it a convenient choice. Explore the area without hassle, with shopping and parks close by.
Guests appreciate the helpful staff and clean accommodations. The hotel’s amenities include a fitness center and business services for those traveling for work.
Relax by the outdoor pool or take a leisurely stroll around the property. It’s a great spot to unwind after a long day.
Choose Comfort Inn & Suites for an enjoyable and comfortable stay in Orangeburg!
Address: 746 Citadel Rd, Orangeburg, SC 29118
6. Fairfield Inn Orangeburg

Experience a warm welcome at Fairfield Inn Orangeburg! This property is loved for its outdoor pool and fitness center, making it perfect for relaxation and exercise.
Guests enjoy complimentary Wi-Fi throughout the hotel. The convenient breakfast offers a variety of choices to start your day right.
Located on Citadel Road, this hotel is just a short drive from local attractions, restaurants, and museums. Explore everything Orangeburg has to offer without any hassle.
Visitors appreciate the friendly staff and clean rooms. The atmosphere invites you to unwind and disconnect from everyday stress.
With everything you need in a warm and inviting setting, Fairfield Inn is ready to be your home away from home.
Address: 663 Citadel Road, Orangeburg, SC 29118
7. Holiday Inn Express & Suites Orangeburg

Holiday Inn Express & Suites Orangeburg provides a comfortable retreat. Guests rating it 3.6/5 appreciate the convenience of free breakfast and an outdoor pool. Enjoy a relaxing stay amidst friendly service.
The hotel features various amenities designed for comfort. Free Wi-Fi is available, keeping you connected throughout your stay. A fitness center is also on-site for those who want to stay active.
It’s located near significant attractions and dining options. Perfect for both business travelers and families, it offers easy access to the surrounding area.
After a long day of exploration, unwind in your cozy room with modern conveniences. Staff members are attentive and eager to assist.
Bring your family or travel for work; Holiday Inn Express & Suites has something for everyone.
Address: 118 Sleep Inn Road, Orangeburg, SC 29118
8. Quality Inn & Suites Orangeburg
Quality Inn & Suites provides a budget-friendly stay. Comfort is key with this hotel, rated approximately $62–$65/night. Enjoy complimentary Wi-Fi and basic amenities.
Guests appreciate the clean and tidy rooms along with a friendly atmosphere. The hotel makes a great base for exploring the nearby area.
It’s conveniently located on Saint Matthews Road, close to local businesses and eateries. Ideal for those on a budget, Quality Inn & Suites offers value without compromising comfort.
Visit local attractions or simply relax in your room with the essentials within reach. Friendly staff members are ready to assist you during your stay.
Book your stay at Quality Inn & Suites for an excellent experience at an affordable price!
Address: 3671 Saint Matthews Road, Building A, Orangeburg, SC 29118
9. Days Inn by Wyndham Orangeburg

Days Inn by Wyndham Orangeburg is perfect for travelers seeking affordable rates. Rated 3.9/5, guests enjoy free breakfast and pet-friendly policies. The hotel aims to provide essential accommodations for all.
Strategically located on St. Matthews Road, it’s close to many attractions. The friendly staff is dedicated to making your stay pleasant and welcoming.
Guests appreciate the cleanliness and convenient facilities. Enjoy a good night’s sleep before continuing your travels.
Relax at the hotel or discover local dining options nearby. Create memories during your stay and enjoy all that Orangeburg has to offer.
For budget-conscious travelers, Days Inn is a reliable choice.
Address: 3691 St. Matthews Rd, Orangeburg, SC 29118
10. Econo Lodge
Welcome to Econo Lodge, where affordability meets convenience! This budget-friendly hotel is perfect for those traveling on a budget. Free breakfast is available to fuel your day of exploring.
Econo Lodge is situated on St. Matthews Road, making it easy to access I-26 and local businesses. Besides essential amenities, the hotel offers comfortable rooms for a restful stay.
Guests appreciate easy access to local attractions and eateries. The atmosphere feels welcoming, and the service provided is friendly and helpful.
Relax after a day of adventures, knowing you have a comfortable space waiting for you. Econo Lodge is an excellent option for value-oriented travelers.
Book your stay at Econo Lodge for a no-frills experience that focuses on customer satisfaction!
Address: 2573 St. Matthews Rd, Orangeburg, SC 29118
11. Motel 6 Orangeburg SC
Motel 6 Orangeburg SC is known for its affordability. With a rating of 3.5/5, it offers basic accommodations perfect for short stays. Rooms are clean, and features include free Wi-Fi for guests.
This motel is conveniently located on Saint Matthews Road, close to restaurants and popular attractions. It provides easy access to I-26, making it ideal for travelers on the go.
Guests enjoy the straightforward service and helpful staff. Whether you’re in town for business or leisure, Motel 6 delivers comfort at a reasonable price.
Relax in a familiar setting. After a day full of activities, unwind in your room comfortably.
Motel 6 is a solid option for those who seek simplicity and efficiency in their travels.
Address: 3671 Saint Matthews Road, Orangeburg, SC 29118
12. Super 8 by Wyndham Orangeburg
Super 8 by Wyndham Orangeburg offers a cozy environment for travelers. This budget hotel features comfortable rooms and free breakfast, making mornings easy and enjoyable.
Conveniently located on Citadel Road, it’s nearby various services and attractions. Guests appreciate the friendly service and clean accommodations.
The hotel also has free Wi-Fi to keep you connected during your stay. Relax in the outdoor areas where you can enjoy fresh air.
Super 8 makes it easy for families and business travelers alike to stay in a friendly and inviting setting. After a busy day, return to your room to unwind and recharge.
Your budget doesn’t have to compromise comfort; Super 8 is proof of that!
Address: 743 Citadel Rd, Orangeburg, SC 29118
13. Red Roof Inn Orangeburg
Red Roof Inn Orangeburg is an affordable option for travelers. With a rating of 3.5/5, it offers all the essentials for a comfortable stay. Pet-friendly options are available, making it welcoming for all guests.
Located on Citadel Road, you’re just moments away from local dining and entertainment. The friendly staff is eager to assist and provide a positive experience.
Guests appreciate clean rooms with modern conveniences. Enjoy free Wi-Fi throughout the property to stay connected while on the road.
Unwind in your room or explore the nearby area after a long day. Red Roof Inn allows you to enjoy affordability without sacrificing quality.
Stay comfortably at Red Roof Inn for a pleasant travel experience!
Address: 732 Citadel Rd, Orangeburg, SC 29118
14. Quality Inn
Quality Inn brings affordable comfort to your travels. Offering clean rooms and basic amenities, this hotel is budget-friendly and offers great value. Many guests report satisfaction during their stays.
The location on Saint Matthews Road makes it easy to reach popular destinations. Free breakfast options cater to all tastes, ensuring you start the day well.
Guests enjoy the friendly atmosphere and helpful staff. Relax in a cozy room after exploring the area or visiting local attractions.
Quality Inn is designed to meet the needs of travelers at an affordable price point. You can expect comfort and convenience without overspending on your stay.
Book your visit to Quality Inn for an enjoyable experience in Orangeburg.
Address: 3671 St. Matthews Rd, Orangeburg, SC 29118
15. Comfort Inn & Suites Santee (nearby)
Comfort Inn & Suites Santee offers a charming experience near I-95, ideal for travelers. The hotel features a pool and fitness center that invites relaxation and activity alike.
Enjoy a free breakfast every morning to keep your energy up. The staff is friendly and always ready to assist with any requests during your stay.
Families love the spacious rooms, making it a perfect choice for group stays. Santee is rich with outdoor activities, allowing you to explore nature and local attractions.
The inviting atmosphere makes you feel right at home. Easy access to major highways helps you visit nearby towns and attractions.
Choose Comfort Inn & Suites for a wonderful stay near stunning Lake Marion!
Address: 139 Brickyard Rd, Santee, SC 29142
16. Hampton Inn Santee (nearby)
Enjoy your stay at Hampton Inn Santee! With an outdoor pool and complimentary breakfast, guests enjoy comfort and convenience. The hotel is located near popular destinations, making it an ideal choice.
The friendly staff ensures a welcoming environment while providing all necessary amenities. Enjoy staying active at the fitness center or relax at the poolside.
Comfortable rooms are designed for relaxation after an adventure-filled day. Santee is known for its beautiful landscapes and nearby recreational areas.
Families and business travelers alike appreciate the quality service at Hampton Inn Santee. It’s the perfect spot to rejuvenate before setting off again!
For your next trip, make Hampton Inn Santee your go-to choice for a delightful experience!
Address: 139 Brickyard Rd, Santee, SC 29142
17. Best Western Santee Inn (nearby)

Welcome to Best Western Santee Inn, where you’ll find comfort and convenience! Located off I-95, it’s perfect for travelers looking for accessibility. This hotel features modern amenities and friendly accommodations.
Guests enjoy free Wi-Fi and breakfast, ensuring you start your day on the right note. The staff is known for their welcoming nature, making each visit pleasant and memorable.
Explore nearby attractions or relax at the hotel in comfort. The rooms are clean and provide ample space for families and business travelers alike.
Best Western Santee Inn awaits to make your journey smoother, with a focus on quality and service.
Choose Best Western Santee Inn for your next adventure and enjoy a delightful travel experience!
Address: 139 B Ricochet Rd, Santee, SC 29142
Final Thoughts
Orangeburg, SC, is home to a wide range of hotels catering to different tastes and budgets. From cozy and budget-friendly options to superior stays with extra amenities, there’s something for everyone. Families, business travelers, and solo adventurers will all find accommodations that suit their needs. If you’re looking for activities during your stay, check out the things to do in Orangeburg for some great suggestions.
Whichever hotel you choose, you’ll experience the warm hospitality of Orangeburg. Make your next trip unforgettable by staying in one of these delightful hotels!